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Sarcoidosis

Sarcoidosis in the Kidney

02/03/2011

Question:

i was told 6 years this May i had sarcoidosis in the kidney. My question is every 6 months during winter my creatine levels goes up and during summer months my levels drops as low as 2.5 is this normal? and i am on a low dose asprin regimen is this good or bad for my sarcoidosis?

Answer:

Dear Sir/Madam - Sarcoidosis can involve the kidneys in several ways. Some cases of sarcoidosis result in over-production of active vitamin D, which causes high levels of calcium in the blood and urine. This can cause direct damage to the kidneys or could result in the formation of kidney stones, which can indirectly damage the kidneys. In other cases, the sarcoidosis actually directly infiltrates the kidneys. Effective treatment of the sarcoidosis usually resolves the high calcium levels and/or reduces the inflammation of the kidneys, which results in improvement of the kidney function.

As for the other questions: The seasonal changes in kidney function are difficult to explain based on the information provided. To my knowledge, the use of low-dose aspirin as a treatment for sarcoidosis has not been tested. Thus, it is difficult to know if this is good or bad for sarcoidosis. Rarely, aspirin can cause inflammation of the kidneys.

A kidney specialist (nephrologist) could help determine why your kidney function is abnormal and why it is fluctuating throughout the year.

For more information:

Go to the Sarcoidosis health topic, where you can:

Response by:

Elliott D Crouser, MD Elliott D Crouser, MD
Associate Professor of Pulmonary, Allergy, Critical Care & Sleep Medicine
College of Medicine
The Ohio State University